For one bag wey be for backyard dirts, scientists don discover one powerful new group of antibiotics wey dem talk say e can wipe out many infections for lab and animal tests, wey include some microbes wey dey resistant to most traditional antibiotics.
Researchers for Rockefeller University in New York don report di discovery of di new antibiotics, wey dem dey call malacidins, on Monday for journal Nature Microbiology .
Dis one be di latest for promising antibiotics wey dem find through innovative genetic sequencing techniques wey dey allow researchers to screen thousands of soil bacteria wey dem no fit grow or study before for dia laboratory. To identify dis new compounds, di Rockefeller researchers go through genetic material and come get 1,500 soil samples.
Sean Brady wey be Biochemist for Rockfeller’s Laboratory for Genetically Encoded Small Molecules talk say,
“We don extract DNA direct from soil samples,”
“We put am into a bug and we can grow am easily for our laboratory and see if we fit make new molecules—wey be di basis of new antibiotics.”
Di new compounds appear to get wahala with di ability of infectious bacteria to build cell walls—wey be function wey dey so basic to cellular life wey dey unlikely dat di microbes fit evolve a way to resist am.
“For di lab tests, bacteria dem expose bacteria to di experimental antibiotics for 21 days and dem no develop resistance,”
As e dey now, di new compounds don appear safe and effective for mice, but but we no get plans yet to submit am for human testing. “e still dey early ” Dr. Brady talk am .